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How are GLPs bad for the world?

>no GLP's

GLPs are similar to gambling?

PFAS (and, to a lesser extent, plasticizers) circulate from the blood to the gut ~5 times per day through enterohepatic circulation (https://en.wikipedia.org/wiki/Enterohepatic_circulation). This is why cholestyramine was shown to be effective at reducing serum PFAS by up to 60% in a Swedish trial.

Blood donations are also somewhat effective, saunas less so. Also, to be clear, PFAS are very different from microplastics. PFAS are the Teflon chemical.

It's a common misconception, but microplastics and forever-chemicals (PFAS) are not the same thing. They're two similar, but distinct pollutants.

> Are saunas and blood donations not also effective for this?

Yes, plasma & blood donations are good at reducing PFAS blood concentration. Some(?) firefighting foam contains PFAS, so they tend to have high blood concentrations. Donations have shown to significantly reduce that: https://pmc.ncbi.nlm.nih.gov/articles/PMC8994130/

Saunas helping with any kind of detox is complete hocum.

Blood donations clearly do.

Microplastics and PFAS aren't synonyms however.

What isn't established is a dose dependant harm from PFAS. Some things are harmful in minute quantities to the point it doesn't matter if you have a lot or a little.

Lead has a clear dose response but a relatively low threshold for noticeable harm. It's not clear what PFAS curve will look like.

I won't restart the linear no threshold flame wars about radiation harm but let's just say it's not always intuitive.

In PFAS's defense, we really needed to poison the whole planet. Otherwise people would have occasionally needed to get wet in the rain, or perhaps scrub their pots and pans. Really, these extremely minor conveniences are worth the devastating cost to ours and future generations.

That's an abstract ideal. In practice, it is not feasible for most people to verify a study. It is difficult enough for colleagues in the field. Hence why we have to use proxies like trustworthiness of a source.

It’s a joke

Most people don't care. PFAS is only voluntarily being phased out in food packaging, rather than being banned. People cook with teflon-coated pans for the tiny convenience over a nitrided, ceramic, or seasoned cast iron pan. Outdoors enthusiasts want PFAS rain jackets and PFAS ski waxes, rather than the alternatives.

I definitely agree they need to look at history, consider what they're being exposed to, and understand how simple and easy some of the substitutions/mitigations could be. There's 0 reason why manufacturers are getting 5+ years to phase out a forever chemical in something like ski wax or dental floss.

Future archaeologists are going to chronicle humankind's stupidity by the lead layer, the atom bomb testing fallout layer, the PFAS layer, etc. All of these were made possible by a misplaced sense of scale. Yes we can poison the whole planet. That little blue dot.

The animal angle is fun and interesting, and my quip about the gloves is mostly a joke. My frustration comes from the fact that we don't (or shouldn't) need to know that PFAS is in Patagonia to care about it.

45% of US households contain PFAS, apparently, but no mitigation or even manufacturing bans are required for years.

In the US, one side cries about regular flouride in the water, but is meh to PFAS. Meanwhile, the other side is supposedly pro-environment, but can't even get the fortitude to ban PFAS ski wax.

you missed the full jab -- "most people" did not care about lead pipes for drinking water. It does not take much effort to blankly state that the public "does not care" and proceed to spend less than one minute of thinking capacity to self-confirm and move on. IMHO That is what you see in some of the comments here -- "ignorance" in true form, on display here in a erudite and modern forum. Functional definition of "ignorance" for this topic? I do not know that and I do not care, end of discussion.